Gamete activation: basic knowledge and clinical applications

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Gamete activation: basic knowledge and clinical applications

BACKGROUND The first clues to the process of gamete activation date back to nearly 60 years ago. The mutual activation of gametes is a crucial event during fertilization. In the testis and ovaries, spermatozoa and oocytes are in a state of meiotic and metabolic quiescence and require reciprocal signals in order to undergo functional changes that lead to competence for fertilization. First, the ...

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ژورنال

عنوان ژورنال: Human Reproduction Update

سال: 2016

ISSN: 1355-4786,1460-2369

DOI: 10.1093/humupd/dmw014